Yellow Fever Vaccine: UN Backs Lower Doses Amid Shortage

تم نشره في Sun 19 June / Jun 2016. 12:00 AM
  • Angolan Mother and Infant, Angola hit hard by a yellow fever outbreak - (Reuters)

ANGOLA — UN health experts have recommended cutting the standard dose of yellow fever vaccine by 80% in emergencies, amid a global vaccine shortage.

A smaller dose would provide immunity for at least 12 months, they said.

Emergency stocks have been depleted by a mass immunisation programme in Angola, where the disease has killed more than 300 people since December.

A surge of cases in the Democratic Republic of Congo has raised fears of a crisis situation.

The current outbreak of the disease has seen 18 million vaccine doses distributed in Angola, DR Congo and Uganda.

The global stockpile of the vaccine has already been depleted twice since February.

A regular dose of the vaccine provides immunity for life. The WHO said it remained unclear whether fractional doses would work for young children.

It said that current vaccine stocks were adequate but an outbreak in DR Congo's populous capital, Kinshasa, meant the strategy was being seriously considered "to prevent transmission through large-scale vaccination campaigns".

DR Congo has reported 1,044 suspected cases of yellow fever since March, including 71 deaths, according to the WHO.

Of 61 confirmed cases, 53 were linked to travel to Angola.

Angola has reported 3,137 suspected cases since December, with 345 deaths reported.

Studies have shown that even vaccine doses of one 10th the regular amount can produce an immune response in healthy adults, Jacqueline Weyer of South Africa's National Institute for Communicable Diseases told the BBC.

"The fear is that yellow fever outbreaks may occur in other locations, or continue to spread, with the consequent need for more vaccine, which cannot be produced in good time," she said.